Thalassemia, also known as Cooley’s Anemia is a genetic disorder, which produces severe anemia due the low production of beta (β)-globin proteins in the hemoglobin molecule of red blood cells. There are two types of thalassemia, alpha (a) thalassemia and beta (β) thalassemia. They are present in Africa, S.E. Asia, Southern China, India, Greece, Italy and the Middle Eastern countries. β thalassemia symptoms include jaundice, extreme fatigue, enlargement of the heart and liver, bone deformation, damage to organs and organ systems. Individuals with β thalassemia are also prone to developing diabetes. Children diagnosed with β thalassemia require regular blood transfusions to maintain good health and survive. a Thalassemia also known as hemoglobin H disease (Hb AH) is a milder condition.